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| Interactions: | Chloramphenicol
Adverse Effect: Decreased antibacterial effectiveness Clinical Management: Monitor signs of clinical effectiveness.
Gentamicin
Adverse Effect: Loss of Gentamicin efficacy Clinical Management: Monitor patients for Gentamicin effectiveness.
Methotrexate
Adverse Effect: an increased risk of methotrexate toxicity Clinical Management: Avoid the concurrent use of methotrexate and penicillin if possible. If concomitant therapy is unavoidable, consider decreasing the methotrexate dose.
Neomycin
Adverse Effect: Loss of Neomycin efficacy Clinical Management: Monitor patients for Neomycin effectiveness.
Netilmicin
Adverse Effect: Loss of Netilmicin efficacy Clinical Management: Monitor patients for Netilmicin effectiveness.
Probenecid
Adverse Effect: Increased penicillin serum levels
Sisomicin
Adverse Effect: Loss of Sisomicin efficacy Clinical Management: Monitor patients for Sisomicin effectiveness.
Streptomycin
Adverse Effect: Loss of Streptomycin efficacy Clinical Management: Monitor patients for Streptomycin effectiveness.
Tetracycline
Adverse Effect: Decreased antibacterial effectiveness Clinical Management: If possible avoid this drug combination. Monitor decreased antibacterial efficacy.
Tobramycin
Adverse Effect: Loss of Tobramycin efficacy Clinical Management: Monitor patients for Tobramycin effectiveness |
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